
I M M U N E T O L E R A N C E I N D U C T I O N S T U D Y
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Welcome to the International Immune Tolerance Study Home Page.
The Study opened for recruitment late in 2002, after a delay due to the shortage of recombinant factor VIII.
The study compares the efficacy, morbidity and cost effectiveness of low versus high-dose
immune tolerance in good-risk patients.
These patients have severe haemophilia A, an inhibitor for 12 months or less and a historical peak inhibitor titre of >
5BU but < 200 units.
The electronic case report form (eCRF) used in the study requires Internet Explorer V4.1 or later.
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Protocol Introduction
Study Objectives and Hypothesis
Contact Information
Posters, latest newsletter and minutes from last meeting
How to join the study
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122 Patients recruited into the study
The next Investigator meeting will be held during the ISTH conference in Boston
Date and time to be confirmed
Enter Electronic C.R.F.
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Web pages developed by: Dr R.A.Hollingsworth